Role of some inflammatory biomarkers in prediction of short-term outcome in acute ischemic stroke

Abstract Background Several factors affect acute ischemic stroke (AIS) outcomes. Objective This study aimed to assess the role of leukocyte count, neutrophil/lymphocyte ratio (NLR), and c reactive protein (CRP) as early predictors outcome in AIS patients. Methods was conducted on 60 They were subjected detailed history taking, clinical examination, brain imaging, laboratory assessment including CRP, white blood cell (WBC) absolute neutrophil count (ANC), lymphocyte (ALC), NLR which is calculated by dividing ANC ALC. Neurological scales used level consciousness Glasgow Coma Scale (GCS) severity National Institute Health Stroke (NIHSS) at first 48 h onset well 1 week 2 weeks later for short-term functional neurological outcome. Results Sixty percent patients had unfavorable outcomes assessed Modified Rankin (mRS). Patients with higher NIHSS scores. positively correlated WBC ANC, CRP. The WBC, NLR, NIHSS, was. Conclusion CRP AIS, more severe poorer are expected.